MRK
Merck & Co., Inc.
NYSE: MRK · Rahway, NJ · Healthcare
$145.27-1.97 (-1.34%)Closed
Market Cap$358.41B
Cash$7.14Bmost recent
Runwayprofitable
P/E (TTM)20.0EPS $7.28
52-Wk Range$80.14 – $155.53
Avg Volume11.3M3-month
Price & Trading Activity
Daily close with catalyst overlays and trading volume
$145.27+46.5%
Pipeline
Drug candidates sponsored by Merck & · ClinicalTrials.gov
| Phase | Drug / Candidate | Indications | Status | Next Completion | Trials | |
|---|---|---|---|---|---|---|
| Phase 4 | MK0869, aprepitant / Duration of Treatment: 3 days | Nausea+1 more | Completed | 2004-09-30past | 1 | |
| Phase 4 | Gonal-f | Infertility | Completed | 2006-01-16past | 1 | |
| Phase 4 | AzaSite (azithromycin ophthalmic solution) | Bacterial Infections+1 more | Completed | 2008-10past | 1 | |
| Phase 4 | Infliximab | Spondylitis, Ankylosing+1 more | Terminated | 2008-11past | 1 | |
| Phase 4 | Nirogacestat | Desmoid Tumor+1 more | Recruiting | 2031-02-26 | 1 | |
| Phase 3 | Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live | Measles+3 more | Completed | 2001-10past | 1 | |
| Phase 3 | Rocuronium bromide (Org 9426) | Muscle Relaxation | Completed | 2003-12past | 1 | |
| Phase 3 | V501 | Human+1 more | Completed | 2005-11-03past | 1 | |
| Phase 3 | Esmirtazapine | Postmenopausal Symptoms+2 more | Completed | 2006-01-15past | 1 | |
| Phase 3 | MK0507A, dorzolamide hydrochloride (+) timolol maleate | Glaucoma+1 more | Completed | 2006-07past | 1 | |
| Phase 3 | Comparator: Quadrivalent Human Papillomavirus (HPV) vaccine | Neoplasms, Glandular and Epithelial+4 more | Completed | 2007-04past | 1 | |
| Phase 3 | Zoster Vaccine, Live, (Oka-Merck) | Varicella Virus Infection | Completed | 2007-05past | 1 | |
| Phase 3 | MK0524A, /Duration of Treatment : 4 Weeks | Flushing | Completed | 2007-08past | 1 | |
| Phase 3 | Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine | Papillomavirus Infections | Completed | 2008-02-04past | 1 | |
| Phase 3 | Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live (ProQuad™) | Measles+3 more | Terminated | 2008-05past | 1 | |
| Phase 3 | Rebif® | Clinically Isolated Syndrome | Completed | 2008-11past | 1 | |
| Phase 3 | Comparator: fosaprepitant dimeglumine | Chemotherapy-Induced Nausea and Vomiting (CINV) | Completed | 2009-06past | 1 | |
| Phase 3 | Acadesine | Coronary Artery Bypass+4 more | Terminated | 2010-10past | 1 | |
| Phase 3 | Sitagliptin phosphate | Type 2 Diabetes | Completed | 2010-10-04past | 1 | |
| Phase 3 | Preladenant 2 mg tablet | Parkinson Disease | Completed | 2012-12-20past | 1 | |
| Phase 3 | CXA-201 | Complicated Urinary Tract Infection+1 more | Completed | 2013-08-11past | 1 | |
| Phase 3 | Ipragliflozin | Type 2 Diabetes Mellitus | Completed | 2017-03-07past | 1 | |
| Phase 3 | V212 | Herpes Zoster | Completed | 2017-04-11past | 1 | |
| Phase 3 | 9vHPV vaccine | Papillomavirus Infections+5 more | Completed | 2019-01-29past | 1 | |
| Phase 3 | Placebo | Chronic Cough | Completed | 2020-06-05past | 1 | |
| Phase 3 | Prevnar 13™ | Pneumococcal Infections | Completed | 2020-12-14past | 1 | |
| Phase 3 | Rotarix™ | Pneumococcal Infections | Completed | 2021-08-05past | 1 | |
| Phase 2 | Pembrolizumab | Non Small Cell Lung Cancer (NSCLC)+8 more | Active, not recruiting | 2027-01-31 | 10 | |
| Phase 2 | Posaconazole oral suspension | Mycoses | Completed | 2001-11past | 1 | |
| Phase 2 | MK0826, ertapenem sodium /Duration of Treatment: 14 Days | Urinary Tract Infections+2 more | Completed | 2003-12past | 1 | |
| Phase 2 | Org 34517 | Depression+2 more | Completed | 2006-07past | 1 | |
| Phase 2 | Sugammadex | Anesthesia, General | Completed | 2006-08-31past | 1 | |
| Phase 2 | MK0533 | Diabetes Mellitus Type 2 | Terminated | 2007-08past | 1 | |
| Phase 2 | MK0893 | Diabetes Mellitus, Type 2 | Terminated | 2008-05past | 1 | |
| Phase 2 | MK0249 | Paranoid Schizophrenia | Completed | 2008-10past | 1 | |
| Phase 2 | UFOX + Cetuximab | Previously Untreated Metastatic Colorectal Cancer | Completed | 2009-06past | 1 | |
| Phase 2 | MK-0941 | Type 2 Diabetes Mellitus | Completed | 2010-05past | 1 | |
| Phase 2 | Vicriviroc | HIV Infections | Completed | 2010-05past | 1 | |
| Phase 2 | Placebo to Ertuglilflozin 1 or 5 mg | Diabetes Mellitus, Type 2+1 more | Completed | 2011-02-09past | 1 | |
| Phase 2 | Cetuximab | Colorectal Neoplasms | Completed | 2014-12past | 1 | |
| Phase 2 | luspatercept | B-Thalassemia | Completed | 2015-11-11past | 1 | |
| Phase 2 | ATX-MS-1467 | Multiple Sclerosis | Completed | 2016-04-30past | 1 | |
| Phase 2 | Grazoprevir | Hepatitis C | Completed | 2016-09-16past | 1 | |
| Phase 2 | Islatravir | HIV-1 Infection | Completed | 2022-03-18past | 1 | |
| Phase 2 | MK-3795 | VHL Gene Mutation+10 more | Completed | 2023-08-30past | 1 | |
| Phase 2 | Olaparib | Solid Tumors | Completed | 2026-06-08past | 1 | |
| Phase 1 | Coformulated favezelimab/pembrolizumab | Metastatic Urothelial Carcinoma+1 more | Active, not recruiting | 2027-05-31 | 1 | |
| Phase 2 | Zilovertamab vedotin | Lymphoma, Large B-Cell, Diffuse | Recruiting | 2027-12-13 | 1 | |
| Phase 2 | Pembrolizumab (+) Berahyaluronidase alfa | Classical Hodgkin Lymphoma Recurrent+3 more | Active, not recruiting | 2028-11-08 | 1 | |
| Phase 1 | coformulation pembrolizumab/quavonlimab | Small Cell Lung Carcinoma | Active, not recruiting | 2029-12-10 | 1 | |
| Phase 2 | Intismeran autogene | Urinary Bladder Neoplasms+2 more | Recruiting | 2031-09-03 | 1 | |
| Phase 2 | Indinavir sulfate | HIV Infections | Unknown | — | 1 | |
| Phase 2 | valopicitabine | Chronic Hepatitis C | Completed | — | 1 | |
| Phase 1 | V520 | HIV-1+1 more | Completed | 2006-10past | 1 | |
| Phase 1 | vorinostat (Suberoylanilide Hydroxamic Acid [SAHA]) in combination with Pemetrexed and Cisplatin | Advanced Cancer | Completed | 2007-12past | 1 | |
| Phase 1 | MK0731 | Cancer | Completed | 2008-01past | 1 | |
| Phase 1 | ridaforolimus | Cancer+1 more | Completed | 2008-07past | 1 | |
| Phase 1 | MK2461 | Advanced Cancer | Completed | 2008-12past | 1 | |
| Phase 1 | Comparator: Testosterone 300 mg, intramuscular injection | Muscle Anabolism | Completed | 2008-12past | 1 | |
| Phase 1 | MK0752 | Healthy | Completed | 2009-01past | 1 | |
| Phase 1 | Comparator: amlodipine besylate | Hypertension | Completed | 2009-02past | 1 | |
| Phase 1 | Comparator: Placebo 5mg (run in) | Alzheimer's Disease | Completed | 2009-10past | 1 | |
| Phase 1 | ACE-031 | Muscular Atrophy | Completed | 2011-02past | 1 | |
| Phase 1 | MK-0873 Patch | Plaque Psoriasis | Completed | 2011-03-01past | 1 | |
| Phase 1 | EMD 1201081 + 5-FU + Cisplatin + Cetuximab | Squamous Cell Carcinoma of the Head and Neck | Terminated | 2011-04past | 1 | |
| Phase 1 | MK-5108 | Cancer, Neoplasms, Tumors | Completed | 2011-04-04past | 1 | |
| Phase 1 | Unnamed | Insomnia | Completed | 2011-09-01past | 1 | |
| Phase 1 | Unnamed | Advanced Pancreatic Adenocarcinoma | Terminated | 2012-05past | 1 | |
| Phase 1 | Vorinostat | Relapsed or Refractory Multiple Myeloma | Completed | 2012-09-03past | 1 | |
| Phase 1 | MK-7680 | Hepatitis C | Completed | 2015-02past | 1 | |
| Phase 1 | PT2385 | Healthy | Completed | 2015-11past | 1 | |
| Phase 1 | Methadone | Human Immunodeficiency Virus (HIV) Infection | Completed | 2016-06-13past | 1 | |
| Phase 1 | Ceftolozane/Tazobactam - Multiple Doses | Critically Ill+1 more | Completed | 2017-06-15past | 1 | |
| Phase 1 | Belzutifan | Healthy | Completed | 2018-05-26past | 1 | |
| Phase 1 | MK-8558 | HIV-1 Infection | Completed | 2020-05-29past | 1 | |
| Phase 1 | MK-6552 | Healthy+1 more | Completed | 2023-11-20past | 1 | |
| Phase 1 | Pembrolizumab Dose C | Melanoma | Completed | 2023-12-04past | 1 | |
| Phase 1 | MK-7602 | Malaria | Completed | 2025-01-06past | 1 | |
| Phase 1 | MK-2225 | Systemic Sclerosis | Completed | 2025-07-14past | 1 | |
| Phase 1 | MK-8527 | Healthy | Completed | 2026-07-31past | 1 | |
| Phase 1 | MK-4082 | Healthy | Completed | 2026-09-01past | 1 | |
| Phase 1 | MK-1403 + additive coformulation | Diabetes Mellitus, Type 2 | Completed | 2026-09-02past | 1 | |
| Phase 1 | MK-4002 | Multiple Myeloma in Relapse+3 more | Active, not recruiting | 2026-12-31 | 1 | |
| Phase 1 | MK-8294 | Metastatic Neoplasm | Recruiting | 2029-07-01 | 1 | |
| Phase 1 | Cyclophosphamide (CPA) | Non-small Cell Lung Cancer (NSCLC) Stage III | Withdrawn | — | 1 | |
| N/A | Unnamed | Arthritis, Rheumatoid | Terminated | 2006-10past | 1 | |
| N/A | PegIntron (peginterferon alfa-2b; SCH 54031) injector | Hepatitis C, Chronic+1 more | Completed | 2009-06past | 1 | |
| N/A | Unnamed | Human Papillomavirus Infection | Completed | 2010-12-13past | 1 | |
| N/A | Unnamed | Infertility | Completed | 2012-01past | 1 | |
| N/A | Unnamed | Colorectal Neoplasms | Completed | 2013-08past | 1 | |
| N/A | Unnamed | Human Papillomavirus Infections | Completed | 2014-12-02past | 1 |
Valuation
Risk-adjusted NPV
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Peer comparison
Cohort check
No peer cohort defined for MRK. Cohorts currently cover gene editing, mRNA, rare-disease gene therapy, and large-cap biotech — more coming soon.