VRTX
Vertex Pharmaceuticals
NASDAQ: VRTX · Boston, MA · Healthcare
$477.36+4.27 (+0.90%)Closed
Market Cap$112.00B
Cash$13.80Bmost recent
Runwayprofitable
P/E (TTM)29.5EPS $14.72
52-Wk Range$366.54 – $529.59
Avg Volume1.5M3-month
Healthstrong

Commercial-stage biotech with a dominant cystic fibrosis franchise, expanding into pain, T1D, and sickle cell via Casgevy.

Price & Trading Activity

Daily close with catalyst overlays and trading volume

$477.36-3.0%
Pipeline

Drug candidates sponsored by Vertex Pharmaceuticals · ClinicalTrials.gov

55 drugs · 100 trials
PhaseDrug / CandidateIndicationsStatusNext CompletionTrials
Phase 4LUM/IVA
Cystic Fibrosis
Completed
2020-10-09past
4
Phase 4Suzetrigine
Acute Pain+1 more
Recruiting
2027-01-30
4
Phase 3telaprevir
Hepatitis C+1 more
Completed
2015-04past
4
Phase 3VX-661/Ivacaftor
Cystic Fibrosis
Completed
2017-02past
1
Phase 3Tezacaftor/Ivacaftor
Cystic Fibrosis
Completed
2018-08-09past
1
Phase 3TEZ
Cystic Fibrosis
Completed
2018-09past
2
Phase 3VX-445/TEZ/IVA
Cystic Fibrosis
Completed
2019-04-24past
1
Phase 3VX-659/TEZ/IVA
Cystic Fibrosis
Terminated
2020-09-09past
1
Phase 3Ivacaftor
Cystic Fibrosis
Completed
2020-10past
12
Phase 3TEZ/IVA
Cystic Fibrosis
Completed
2020-10-28past
2
Phase 3LUM
Cystic Fibrosis
Completed
2021-10-29past
1
Phase 3VX-121/TEZ/D-IVA
Cystic Fibrosis
Completed
2023-05-12past
3
Phase 3Suzetrigine (SUZ)
Acute Pain
Completed
2023-08-25past
1
Phase 3IVA
Cystic Fibrosis
Completed
2023-10-02past
3
Phase 3ELX/TEZ/IVA
Cystic Fibrosis
Completed
2026-01-29past
8
Phase 3VX-880
Diabetes Mellitus, Type 1+2 more
Recruiting
2027-06-30
1
Phase 2CTX001
Beta-Thalassemia+6 more
Active, not recruiting
2027-11-14
3
Phase 3VNZ/TEZ/D-IVA
Cystic Fibrosis
Completed
2029-07-30
2
Phase 2biricodar dicitrate
Lung Cancer
Terminated
2001-02past
1
Phase 2Ribavirin
Chronic Hepatitis C
Completed
2008-05past
1
Phase 2VX-809
Cystic Fibrosis
Completed
2011-05past
3
Phase 2telaprevir or matching placebo
Hepatitis C+1 more
Completed
2012-03past
1
Phase 1VCH-222 or matching placebo
Hepatitis C
Completed
2012-09past
1
Phase 2VX-787
Influenza Virus
Completed
2012-10past
1
Phase 2Lumacaftor
Cystic Fibrosis
Completed
2014-04past
1
Phase 2VX-135
Chronic Hepatitis C+3 more
Completed
2014-05past
2
Phase 2VX-509
Rheumatoid Arthritis
Completed
2014-07past
1
Phase 2VX-661
Cystic Fibrosis
Completed
2016-05-27past
2
Phase 2VX-121
Cystic Fibrosis
Completed
2019-12-10past
1
Phase 2VX-814
Alpha 1-Antitrypsin Deficiency
Terminated
2020-11-14past
1
Phase 2VX-864
Alpha1-Antitrypsin Deficiency
Completed
2021-05-04past
1
Phase 2VX-548
Acute Pain+1 more
Completed
2023-06-08past
2
Phase 1VX-264
Type 1 Diabetes
Active, not recruiting
2027-03-12
1
Phase 2VX-993
Acute Pain+2 more
Recruiting
2027-03-25
4
Phase 2Povetacicept
Myasthenia Gravis, Generalized
Recruiting
2029-03-02
1
Phase 1VCH-759 (BCH-27759)
Hepatitis C, Chronic
Completed1
Phase 1VCH 916
HCV Infection
Completed
2008-10past
1
Phase 1VX-770
Cystic Fibrosis
Completed
2010-03past
2
Phase 1Prednisone
Drug Interactions
Completed
2013-08past
1
Phase 1VX-440
Cystic Fibrosis
Completed
2016-09-14past
1
Phase 1VX-840
APOL1-mediated Kidney Disease
Completed
2022-11-07past
1
Phase 1VX-708
Pain
Completed
2023-03-07past
1
Phase 1VX-634
Alpha 1-Antitrypsin Deficiency
Completed
2023-05-24past
1
Phase 1Vanzacaftor
Cystic Fibrosis
Completed
2023-06-14past
1
Phase 1VX-147
Focal Segmental Glomerulosclerosis (FSGS)
Completed
2023-09-02past
1
Phase 1IXP
Focal Segmental Glomerulosclerosis (FSGS)
Completed
2024-12-20past
1
Phase 1VX-150
Pain
Completed
2025-03-22past
1
Phase 1VX-828
Cystic Fibrosis
Active, not recruiting
2026-07-16past
1
Phase 1VX-581
Cystic Fibrosis
Recruiting
2026-11-19
1
Phase 1AVN-944 capsules for oral administration
Acute Leukemia+5 more
Completed1
N/AIvacaftor Exposed
Cystic Fibrosis
Completed
2016-05past
1
N/AUnnamed
Cystic Fibrosis
Completed
2019-12past
1
N/AUnnamed
Cystic Fibrosis
Completed
2021-12-20past
1
N/AUnnamed
Cystic Fibrosis
Completed
2025-11-27past
1
N/AUnnamed
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Active, not recruiting
2026-12-31
1
Valuation

Risk-adjusted NPV

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Peer comparison

Cohort check

Large-cap biotech · 5 tickers
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Cells tinted green are top-ranked in the cohort, red are worst-ranked.